Help! Gyno is killing me!!

[MullacT]

Alright. Had it for a few years and am wanting to toast it so I have a shred of confidence with my shirt off. Letro sounds like the only way. Would a doctors prescription be easy to come by as a male? Any help appreciated. 

 

Chur

[maccaz]

2 minutes ago, MullacT said:

Alright. Had it for a few years and am wanting to toast it so I have a shred of confidence with my shirt off. Letro sounds like the only way. Would a doctors prescription be easy to come by as a male? Any help appreciated. 

 

Chur

if you've had it for a few years it may be worth looking at getting it cut out, i thought letrozone can only reduce it a little if at all once the growths actually happened (no science brah, just based on other reports on this forum so please correct me if wrong)

[Daz69]

Hi There, this is what endocrinologists currently advise as treatment for gynecomastia:

 

TREATMENT

Treatment of the underlying endocrinologic or systemic disease that has caused gynecomastia is mandatory. Testicular tumors, such as Leydig cell, Sertoli cell or granulosa cell tumors should be surgically removed. In addition to surgery, germ cell tumors are further managed with chemotherapy involving cisplatin, bleomycin and either vinblastine or etoposide. Should underlying thyrotoxicosis, renal or hepatic failure be discovered, appropriate therapy should be initiated. Medications that cause gynecomastia should also be discontinued whenever possible based on their role in management of the underlying condition. The improvement should be apparent within a month after discontinuation of the culprit drug. If the gynecomastia persists for more than one year, complete regression is unlikely because of the presence of less reversible fibrotic tissues. Of course, if a breast biopsy indicates malignancy, then mastectomy should be performed.

If no pathologic abnormality is detected, then appropriate treatment is close observation. A careful breast exam should be done initially every 3 months until the gynecomastia regresses or stabilizes, after which a breast exam can be performed yearly. It is important to remember that most cases of pubertal gynecomastia may resolve spontaneously within one to two years, around 20% of patients have residual gynecomastia by the age of 20. Information about gynecomastia should be provided for those patients who are interested to know more about their conditions.

MEDICAL TREATMENT

If the gynecomastia is severe, does not resolve, and does not have a treatable underlying cause, some medical therapies may be attempted. There are 3 classes of medical treatment for gynecomastia: androgens (testosterone, dihydrotestosterone, danazol), anti-estrogens (clomiphene citrate, tamoxifen) and aromatase inhibitors such as letrozole and anastrazole.

Once gynecomastia is established, testosterone treatment of hypogonadal men with gynecomastia often fails to produce breast regression. Unfortunately, testosterone treatment may actually produce the side effect of gynecomastia by being aromatized to estradiol. Thus, although testosterone is used to treat hypogonadism, its use to specifically counteract gynecomastia is limited. Dihydrotestosterone, a non-aromatizable androgen, has been used in patients with prolonged pubertal gynecomastia with good response rates. Since dihydrotestosterone is given either intramuscularly or percutaneously, this may restrict its usefulness. Danazol, a weak androgen that inhibits gonadotropin secretion, resulting in decreased serum testosterone levels, has been studied in a prospective placebo-controlled trial, whereby gynecomastia resolved in 23 percent of the patients, as opposed to 12 percent of the patients on placebo. The dose used for gynecomastia is 200 mg orally twice daily. Unfortunately, undesirable side effects including edema, acne, and cramps have limited its use.

Investigators have reported a 64 percent response rate with 100 mg/day of clomiphene citrate, a weak estrogen and moderate anti-estrogen. Lower doses of clomiphene have shown varied results, indicating that higher doses may need to be administered, if clomiphene is to be attempted. Tamoxifen, also an anti-estrogen, has been studied in 2 randomized, double-blind studies in which a statistically significant regression in breast size was achieved, although complete regression was not documented. One study compared tamoxifen with danazol in the treatment of gynecomastia. Although patients taking tamoxifen had a greater response with complete resolution in 78 percent of patients treated with tamoxifen, as compared to only a 40 percent response in the danazol-treated group, the relapse rate was higher for the tamoxifen group. Although complete breast regression may not be achieved and a chance of recurrence exists with therapy, tamoxifen, due to relatively lower side effect profile, may be a more reasonable choice when compared to the other therapies. If used, tamoxifen should be given at a dose of 10 mg twice a day for at least 3 months. Responders usually improve with reduced pain within 1 month. Another anti-estrogen, raloxifene has also been used in the treatment of pubertal gynecomastia but its efficacy needs to be evaluated in randomized prospective studies.

An aromatase inhibitor, testolactone, has also been studied in an uncontrolled trial with promising effects. Further studies must be performed on this drug before any recommendations can be established on its usefulness in the treatment of gynecomastia. Newer aromatase inhibitors such as anastrozole and letrozole may have therapeutic potential, but recent randomized, double-blind, placebo-controlled trials have not confirmed its efficacy. In a study involving patients receiving bicalutamide therapy for prostate cancer, only tamoxifen, but not anastrozole, significantly reduced the incidence of gynecomastia/breast pain when used prophylactically and therapeutically. In another study on pubertal gynecomastia, no significant difference was demonstrated between the anastrozole and placebo groups in patients suffering from pubertal gynecomastia.

From various series, some patients with gynecomastia show no significant improvement after medical treatment. This may be related to the stage of disease at which medical treatment is initiated. It has been suggested that the patient with a long history of gynecomastia, in which the breast tissue becomes fibrotic, tends to be resistant to medical treatment.

 

SURGICAL TREATMENT

When medical therapy is ineffective, particularly in cases of longstanding gynecomastia, or when the gynecomastia interferes with the patient's activities of daily living, or when there is suspicion of malignancy of breast, then surgical therapy is appropriate. On the other hand, surgical treatment should be postponed in pubertal gynecomastia, preferably until after completion of puberty, so as to minimize the chance of recurrent gynecomastia after surgery. Surgical treatment includes removal of glandular tissue coupled with liposuction, if needed, preferably with individualized approach. Nowadays, minimally invasive surgery is available and it may be associated with few complications and prompt recovery. Of note if malignancy is suspected, histological examination is mandatory. Uses of delicate cosmetic surgical techniques are warranted to prevent unsightly scarring.

[nate225]

Letro is a last ditch attempt before surgery, worth a try. 

One guy I know swears by breaking the lumps up! I've never had gyno except as a teenager but f*ck that's sounds brutal!

[maccaz]

5 minutes ago, nate225 said:

Letro is a last ditch attempt before surgery, worth a try. 

One guy I know swears by breaking the lumps up! I've never had gyno except as a teenager but f*ck that's sounds brutal!

 wow thats nuts.

 

was it @PETN on here that was considering a home job surgery? fck that haha

[woody]

nova for me clears up the early onset of gyno without fail.but a few years in your only real option is surgery with a cost of 8 to 10 g.

[jimmybro1]

Home surgery. 

 

Simple cut nips off remove breast tissue then sow nips back on 

[maccaz]

1 hour ago, jimmybro1 said:

Home surgery. 

 

Simple cut nips off remove breast tissue then sow nips back on 

Simple as that 

[woody]

important to label left and right upon removal.