how important is pct on test e only cycle.

[1MoreRep]

Hi guys

 

been awhile since I've posted something on here.

planning to start a test E only cycle and have my hands on 20 ampules of pharm grade 200mg/ml  gelenika test E

that I've been saving for the last 2 years for the right time.

 

I've spoken to some guys and hey say its not necessary to use pct  at that low dose?

 

is that true what they say?

[maccaz]

you didnt state what dose you are going to run? And for how long ?

[Kalidane]

As above, plus individual variance.

 

Normalising endocrine functions after a cycle as quickly as possible sounds good though right?

[1MoreRep]

Well was thinking either 200mg for 20weeks or 400mg for 10 weeks.

[maccaz]

Go 500 for 12-25 weeks

Do pct

[kingersman]

Why pct? 500 is low enough to taper and still recover from? Save the money for other stuff imo

[yeelang]

you want pct on every cycle,

 

recovering and returning to normal function as fast as possible is going to hold the most gains

[Daz69]

Well was thinking either 200mg for 20weeks or 400mg for 10 weeks.

 

20 weeks is a bit long to stay on for maximal effects, Initially, there is an up-regulation of the AR but after sustained elevated testosterone levels some desensitization occurs which leads to a decrease in mRNA levels acting as a negative feedback loop. In several cases it was found that the AR content increased but the binding affinity for androgens decreased resulting in a net loss of testosterone utilization. Essentially, after such a long period of exposure the extra testosterone (above a certain point) became useless, whereas initially when first starting a cycle the extra free testosterone resulted in an almost linear dose-dependent effect curve. So, there's still benefit to an extended cycle (longer than 12 weeks) but the growth experienced isn't near what one expects an the beginning of a cycle... almost a sort of plateau effect. Leaving a 3 month gap or so between cycles resulted in a stronger initial response to the androgens...

[kingersman]

Daz do we/anyone know what that certain point of extra testosterone is? Or does it vary according to genitics and muscle mass?

[Daz69]

Daz do we/anyone know what that certain point of extra testosterone is? Or does it vary according to genetics and muscle mass?

 

I would have thought very low, close to normal endogenous levels, with slight variations due to body size and individual genetics...

I have asked this question of a friend conducting research into exercise physiology and biochemistry I am awaiting a response...

[yeelang]

20 weeks is a bit long to stay on for maximal effects, Initially, there is an up-regulation of the AR but after sustained elevated testosterone levels some desensitization occurs which leads to a decrease in mRNA levels acting as a negative feedback loop. In several cases it was found that the AR content increased but the binding affinity for androgens decreased resulting in a net loss of testosterone utilization. Essentially, after such a long period of exposure the extra testosterone (above a certain point) became useless, whereas initially when first starting a cycle the extra free testosterone resulted in an almost linear dose-dependent effect curve. So, there's still benefit to an extended cycle (longer than 12 weeks) but the growth experienced isn't near what one expects an the beginning of a cycle... almost a sort of plateau effect. Leaving a 3 month gap or so between cycles resulted in a stronger initial response to the androgens...

 

yeah this is why I tell guys to taper up and taper down, I haven't seen research on AR desensitization, but there is research that ATCH cortisol and myostain increase in linear fashion as AAS dose increases. 

 

If I could do it all again I would start on 250mg and taper up until my bloods got too out of wack then taper back down again

[Leeroid]

Some really interesting discussion in this thread. Learning a lot!

[1MoreRep]

yeah this is why I tell guys to taper up and taper down, I haven't seen research on AR desensitization, but there is research that ATCH cortisol and myostain increase in linear fashion as AAS dose increases.

If I could do it all again I would start on 250mg and taper up until my bloods got too out of wack then taper back down again

How would u taper with 20x 1ml ampules of 250mg/ml test E?

[Boosting]

How would u taper with 20x 1ml ampules of 250mg/ml test E?

Decrease injection frequency or amount injected at a time or both. To decrease amount per pin buy/obtain a sealed sterile vial and put a couple of your ampules of oil into it and then pin less than 1ml at a time. Or just use a syringe and small diameter long needle with cap replaced in airtight container fridge. It baffles me that people cant come up with this stuff themselves.

[Pseudonym]

I would have thought very low, close to normal endogenous levels, with slight variations due to body size and individual genetics...

So how would that affect people on cruise/blast?

[Realtalk]

Decrease injection frequency or amount injected at a time or both. To decrease amount per pin buy/obtain a sealed sterile vial and put a couple of your ampules of oil into it and then pin less than 1ml at a time. Or just use a syringe and small diameter long needle with cap replaced in airtight container fridge. It baffles me that people cant come up with this stuff themselves.

Sounds like too much fucking around for me. Long estered steroids essentially taper down themselves. I wouldn't even bother taping off 250mg lol what a waste of time.

Which is really why the old "start pct 3 weeks after last shot" kind of lacka logic, while we are on the subject of pct... So people wait 3 weeks whether they are on 250mg a week or 1250mg a week....? Bit stupid.

I would taper on a bigger cycle but not to the extreme some people take it. But on 250mg/week I wouldn't bother.

[Boosting]

Agree^

He asked how though. I wouldn't bother trying to taper unless i was coming off gear fully and only if using much higher doses of test and/or multiple compounds. In these cases pinning test only for a month or so after other compounds seems to go pretty well. Less sides and not as much loss of gains. Thats my experience anyway.

[yeelang]

How would u taper with 20x 1ml ampules of 250mg/ml test E?

 

 

with only that much test it's probably not worth tapering up. Usually at around the 8 week mark first cycle uses start to notice a decrease in results on 500mg/week test. I would still taper down though. Going from 500mg/week to zero test has 1-2 brutal weeks without hcg.

[1MoreRep]

Damn that sounds complicated alright for first cycle lolz anyone here local from south auckland wanna show me the ropes in person LOLz

[Realtalk]

Damn that sounds complicated alright for first cycle lolz anyone here local from south auckland wanna show me the ropes in person LOLz

It's not complicated at all mate.