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A pill a day keeps the lard away - without exercise


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A pill a day keeps the lard away - without exercise

Wednesday May 02, 2007

By Jeremy Laurance

http://www.nzherald.co.nz/section/story ... d=10437196

American scientists have discovered an "exercise pill" that switches on a gene that tells cells to burn fat.

The unnamed drug, which is in the early stages of development, could offer an answer to the obesity crisis.

Researchers who tested it in mice said it stopped the mice putting on weight even when fed a high-fat diet. The drug triggers the same fat-burning process that occurs during exercise, even when the mice are not active. By kickstarting the metabolism, more calories are burnt than are consumed.

Ronald Evans, a researcher at the Salk Institute in California, said he hoped that such "metabolic trickery" would lead to new treatments for human metabolic syndrome, a condition marked by obesity, high blood pressure and high cholesterol, which raises the risk of heart disease and diabetes.

He presented his findings to a conference of the American Society for Biochemistry and Molecular Biology in Washington, on Monday.

Existing drugs for obesity work by reducing appetite or stopping fat from being absorbed.

In earlier research, Dr Evans identified the receptor that tells cells when to burn fat, when to store it and regulates muscle development. Through genetic engineering, he created mice born with an innate resistance to weight gain and twice the normal physical endurance.

Now Dr Evans and colleagues have found a drug that can activate the receptor switch in fat cells temporarily, opening up the possibility of a one-a-day pill for fully grown adults who needed to increase their energy expenditure and lose weight.

"Too few people get an ideal amount of exercise," he said. "Having access to an exercise pill would improve the quality of muscles, and increase the burning of energy or excess fat [lowering] the risks of heart disease and diabetes."

- INDEPENDENT

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:roll:

That's so dumb. Obese people just need an education pill. Just friggin exercise and don't eat insane amounts of crappy food. And on that note, I bet that these people will get into an 'eat whatever whenever because the pill lets me' mentallity. There's a hell of a lot more bad sides to eating crap food than just putting on fat. And where does that energy go? Most probably released as heat. Calories apon calories of extra body heat cannot be good for you.

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"Having access to an exercise pill would improve the quality of muscles, and increase the burning of energy or excess fat [lowering] the risks of heart disease and diabetes."

..ahh can anyone explain to me exactly wat that means..? and how so? ahaha

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  • 2 weeks later...
:roll:

That's so dumb. Obese people just need an education pill. Just friggin exercise and don't eat insane amounts of crappy food. And on that note, I bet that these people will get into an 'eat whatever whenever because the pill lets me' mentallity. There's a hell of a lot more bad sides to eating crap food than just putting on fat. And where does that energy go? Most probably released as heat. Calories apon calories of extra body heat cannot be good for you.

Im with you Zero. This pisses me off. This is going to give overweight people a reason to not give a shit. oops am i allowed to say the 's' word?

I have an overweight friend (obese) who uses the excuse 'i just dont have the motivation you do' or 'your so lucky, bla bla bla', im like thats crap! if they got off their lazy asses and did the simpliest of exercise like walking then they might not feel so bad, its just bloody lazy. These people dont need a miracle they need someone to staple their mouths shut!

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If it was as good as stated i would try them, why not a pill that burns fat ? sounds good to me dont many body builders already do this? I am very skeptical however that this would work better than what is currently out there.

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