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Follistatin .... Steroids will be superseeded?


Optimass

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Follistatin is being studied for its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive muscle growth. Lee & McPherron demonstrated that inhibition of GDF-8, either by genetic elimination (knockout mice) or by increasing the amount of follistatin, resulted in greatly increased muscle mass. In 2009, research with macaque monkeys demonstrated that regulating follistatin via gene therapy also resulted in muscle growth and increases in strength. This research paves the way for human clinical trials, which are hoped to begin in the summer of 2010 on Inclusion body myositis.

A study has also shown that increased levels of follistatin, by leading to increased muscle mass of certain core muscular groups, can increase life expectancy in cases of spinal muscular atrophy (SMA) in animal models.

It is also being investigated for its involvement in polycystic ovary syndrome (PCOS), though there is debate as to its direct role in this infertility disease.

A break through in this technology could change the face of body building and sports as a whole. Where do we sign up for trials? :D

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keeen lol this sounds like some serious bzznzz.

people more muscular then Gary Coleman? Cutler? cant tell if this is gonna look good or if the bodybuilders of the future will look like walking tumors n_n

There are already peeps around who look like walking tumors! :pfft:

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