Tren gyno halp

[thatwaslight]

What drug, how much?

Running 250 test, 400 tren e

Is adex going to help? have letro also but I didn't find it be particularly effective last time.

[Dreadmouse]

have you had blood tests? that should tell you whats causing the problem and you can go from there.

[jimmybro1]

What drug, how much?

Running 250 test, 400 tren e

Is adex going to help? have letro also but I didn't find it be particularly effective last time.

Aren't you taking finisteride? 

 

Could this potentially be the cause? 

[atrollappears]

What drug, how much?

Running 250 test, 400 tren e

Is adex going to help? have letro also but I didn't find it be particularly effective last time.

 

By gyno, what are your symptoms..? Generally if estrogen is managed gyno shouldn't be a problem, but in your case it is, so its obviously a concern, and something else is at play..

Tren-E should be pinned more frequently than once a week..

 

Tren doesn't aromatise, so adex won't be any help..

 

Nolvadex or Raloxifine  (more so) is advised for gyno symptoms ...

 

Aren't you taking finisteride? 

 

Could this potentially be the cause?

 

 

This could be an issue by lowering Androgen:Estrogen ratio..!!!!!!

 

Answer my PM..!!

[atrollappears]

To further add:

 

Gynecomastia?

 

Almost 25% of all cases of gynaecomastia are currently classified as idiopathic. In this group of patients, circulating sex hormones, SHBG and gonadotrophins are within reference limits. The development of gynaecomastia is attributed to an altered tissue response which may be due to reduction in androgen receptors and/or a local increase in aromatase activity in the breast. Reduction in androgen receptors may be congenital or induced by drugs.

Ann Clin Biochem 2001; 38: 596-607

The effects of progesterone, namely reduced levels of DHT and elevated SHBG may be integral to any role in gyno formation.

Here's another quote that I think is relevant (but I don't know the original source) talks about the contribution of DHT levels:

 

"In addition to elevated IGF-1, lowered DHT levels resulting from endogenous testosterone suppression may contribute to gyno from non aromatizing steroids. Gyno is a reported side effect from finasteride use. Some have attributed this to elevated estrogen levels due to the fact that there is more testosterone to be aromatized, since less test is being converted to DHT. Other researchers think that DHT has a direct antiestrogenic effect on breast tissue.

Studies have shown that DHT can actually block estrogen from binding to the estrogen receptor in mammary tissue. DHT also is an aromatase inhibitor. Even more interesting is the fact that transdermal DHT cream has been used successfully to treat gyno.

It may be that the estrogen/DHT ratio is more important to the development of gyno than the estrogen/testosterone ratio."

So what may be happening is:

 

1) Progestin/progesterone ---> increased progesterone receptor signaling (which leads to) --> increased IGF-1 expression ----> stimulation of alveolar hyperplasia (not sure exactly how much this contributes to gyno)

 

2) Progestin/progesterone ---> increased progesterone receptor signaling--> lowered DHT levels ---> decreased antiestrogenic DHT activity in breast tissue = decreased DHT block of estrogen receptors in breast AND decreased DHT anti-aromatase activity in breast

 

The question that must be asked for each individual androgen is how much relative progestational activity does it have.

For example if nandrolone blocks DHT formation more so than trenbolone, but trenbolone elevates SHBG more than nandrolone, the relative importance of these effects will determine which compound is more likely to lead to gyno. By most accounts, nandrolone is more effective at this (especially when combined with test, which likely results in elevated estrogen at the same time), suggesting that the effects on DHT are more critical.

 

Its fatty tissue for the most part, so dieting will surely help. Some people have also had great success using andractim gel applied directly to the gyno.

 

Tren appears to be a mild-anti-progestin, showing all the signs of lower progesterone including reduction of body-fat and pulmonary stamina. So could indeed be you are sensitive to the anti-estrogenic effect of progestins in the breast, where deca actually protects you a bit more, where tren might expose you a bit more. The switch from one to the other would then indeed cause the most profound effect. Ideally you will want to lower test when using tren, or opt to increase androgenic compounds, as is often the case with tren:mast combo's. Neither should have an effect at lower levels of estrogen though.

 

Hope this helps....

[yeelang]

I personally don't run Deca, there was a human study that showed 300 Deca vs 300 test, test was slightly better ( although more shutdown, more estrogen) while the results were pretty similar I would rather not run a progesterone if I don't need to. SERM/AI will solve all your issues with a test based stack.. why mess around with drugs risks you can't mitigate.

 

 

 

 

re tren, I personally like to run test at 250-300mg and run more tren, much rather 250mg test 750mg tren, than 500mg of each.

 

Less sides (sleep, swet) less gyno risk, only thing to be more careful with is LDL and hydration. You can also eat a lot of carbs on that dosage and fat gain is minimal if you keep your fat and carb meals separated 

[Realtalk]

I personally don't run Deca, there was a human study that showed 300 Deca vs 300 test, test was slightly better ( although more shutdown, more estrogen) while the results were pretty similar I would rather not run a progesterone if I don't need to. SERM/AI will solve all your issues with a test based stack.. why mess around with drugs risks you can't mitigate.

 

 

 

 

re tren, I personally like to run test at 250-300mg and run more tren, much rather 250mg test 750mg tren, than 500mg of each.

 

Less sides (sleep, swet) less gyno risk, only thing to be more careful with is LDL and hydration. You can also eat a lot of carbs on that dosage and fat gain is minimal if you keep your fat and carb meals separated

You ever gonna post a pic or tell us how much you lift bro?

[crazyfacials]

OP you know the drill....pics of gyno or neg train