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Arimidex // Water - possible retarded question inside.


donz

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So was reading some Phil Heath diet thread which was then spammed with his "supposeded" cycle - anyways a part of this got me wondering, is the amount of adex or other AI type stuff dependant on how much gear you'd be using? Because in one post some random douche said "and leading up he'd be using about 3mg of adex a day" - obviously taking advice or info from a random on reddit to heart is stupid but then being a classic over thinking and over analising nerd that I would ask on here anyway.

Currently I just use 1mg every Mon/Wed/Fri pretty much - If this was say 1mg a day, or 2mg a day - does anyone have any idea if this would actually drop more water or remain the same? I tried googling but really couldn't find any solid literature on how it works especially in conjuction with guys/bodybuilding - lots of lit on breast cancer etc D:!

<3

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As far as I know, it is dose dependent. By my logic, the body produces aromatase enzymes to attach to testosterone molecules in the bloodstream in order to convert the excess into estrogen. The more testosterone you use, the more aromatase enzymes your body produces. Since the job of an Aromatase Inhibitor is to attach to these aromatase enzymes and render them useless, it makes sense to me that the more AI you use, the more of these 'soldiers' (AI) you will have to fight the 'enemies' (aromatase enzymes). Pardon the crude analogy.

 

But you do want a bit of estrogen to be created so that's why you don't use too much AI. Low or no estrogen sides include sore joints, lethargy, depression, no gains etc. Come comp time though, your main priority is to eliminate all possible causes of water retention, estrogen would be one of the first things you'd target. Then it would make sense to use as much AI as possible to incapacitate every single aromatase enzyme that your body makes.

 

Of course this may or may not cause you to drop water, you will notice a difference if the cause of your water retention IS estrogen related but if you naturally don't produce much aromatase enzymes anyway or the cause of your water retention is from other reasons (diet, stress, sickness etc) then it won't make much difference.

 

I don't know if my reply was at all related to what you were asking but hopefully that helps.

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Shoulda just msgd you on FB before I posted really, fkn wizard.

Hell, no! If everyone did that, there'd be no Gymnation community. This way everyone can benefit from the answers. :)

 

 

The more testosterone you use, the more aromatase enzymes your body produces.

Good reply, Leeroid. Are there studies proving that ^ as fact, or is it an extension of your logic? I'm not disagreeing with it at all (certainly seems logical) but it's the point your whole explanation hinges on, so I wondered how solid it is.

 

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Hahah sorry! You know I check here daily and love the input, actually its the only forum on gymnation I read cos I love you big kents! 

What Leedawg said is what I "thought" made sense when I was thinking in my head about the more you use/pin the more of the other would be produced but like I said I couldn't find it to back it up and I'm too inexperienced to just believe my own "brah it makes sense" thoughts cos I've had way to many moments for that. 

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The more testosterone you use, the more aromatase enzymes your body produces.

Good reply, Leeroid. Are there studies proving that ^ as fact, or is it an extension of your logic? I'm not disagreeing with it at all (certainly seems logical) but it's the point your whole explanation hinges on, so I wondered how solid it is.

 

yeah im also curious about this. i was under the impression that your body just produced a certain amount of the enzyme and that higher doses just meant more enzyme inactive = less estrogen produced.

would have assumed pros used higher dosages of an AI just to make sure theres no estrogen left, not because more test = more enzyme = higher dose required.

 

 

 

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Well, your body does make aromatase enzymes naturally even when you don't administer exogenous androgens. And the endocrine system can't differentiate between exogenous and natural testosterone. So the only difference is that plasma testosterone levels are higher.

 

The previous statement is fact but what follows is only theoretical. Since the body likes to maintain a balance in hormones, if the body detects a high level of androgens, it seems only logical to me that the body would respond by increasing it's production of aromatase in order to convert the excess testosterone into estrogen, thus maintaining the test:estrogen ratio. Plus Wikipedia said this: "Aromatase is localized in the endoplasmic reticulum where it is regulated by tissue-specific promoters that are in turn controlled by hormones, cytokines and other factors". Hormones being the keyword there. However, I realise that Wikipedia can be unreliable.

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Hahah well I've read enough to make me curious and just add more at the end of what I'm doing - might work, might not and won't know til then or if at all but it's cheap enough that it's no biggy either way :D

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