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  1. Cenforce 100 mg Tablet should be taken once a day with water. The tablet is Cenforce 100, which means it dissolves quickly and fizzes in water. Drink it as soon as it dissolves for a better flavor and faster absorption of the medicine into the body. Although there is no evidence that Cenforce interacts with food, it is best to take the tablet on an empty stomach. You should also keep in mind that the Cenforce and Fildena 100 mg should be administered one to thirty minutes before sexual activity. It is necessary to have sexual stimulation for Sildenafil to work. In the absence of sexual excitement, the medication will not work.